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What need to be carried out for someone with indications and signs of a probable opioid overdose or an overdose involving opioids and xylazine?

When responding to an overdose, administering naloxone and supplying “rescue breaths” can reverse the effects of fentanyl in somebody’s program. If xylazine can be concerned, the naloxone might hold the person alive by resuming their breathing, but They might remain sedated and unconscious.

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Almost all of the prevailing research on xylazine was conducted in animal experiments as human trials had been shut down. Scientists continue to Possess a good deal to learn about xylazine, including its addictive properties and withdrawal effects, Sue stated.

Should you suspect anyone has overdosed on xylazine, contact emergency health-related solutions at once. Even though there is no cure for xylazine itself, other treatment plans could possibly be utilised.

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Regretably, growing consciousness of xylazine has contributed to The parable of “naloxone-resistant” overdoses. Not like overdoses with opioids only, individuals suffering from xylazine-related overdoses may well not promptly get up immediately after naloxone administration. Though naloxone may well not reverse the effects of xylazine, it is still capable of reverse the effects of the fentanyl it is often mixed with and should be Employed in all suspected opioid overdoses.

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